HitPredict

Interactor 1: RYR1 (P21817)
Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)
Gene: RYR1

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 5038 Hs			1 317
+	Hs
		818041 ITPR2_HUMAN (4781-5024): 1.06e-99: 364: 31.62		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818559 ASH2L_HUMAN (919-1226): 3.86e-56: 211: 18.44		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818100 HNRL2_HUMAN (955-1234): 2.07e-53: 205: 18.77		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818375 RANB9_HUMAN (1008-1308): 4.75e-52: 201: 17.34		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818174 RBP10_HUMAN (1020-1309): 8.51e-51: 194: 16.03		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818305 DDX1_HUMAN (1020-1216): 4.57e-46: 183: 16.42		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		1332327 ASH2L_HUMAN (919-1226): 3.86e-56: 211: 18.44		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		1301799 RANB9_HUMAN (1008-1308): 4.75e-52: 201: 17.34		HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32
+	Hs
		996696 HNRL2_HUMAN (955-1234): 2.07e-53: 205: 18.77		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		1301814 RANB9_HUMAN (1008-1308): 4.75e-52: 201: 17.34		HM20B_HUMAN (11-249): 2.15e-33: 126: 17.77
+	Hs
		1266106 DDX1_HUMAN (1020-1216): 4.57e-46: 183: 16.42		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26