HitPredict

Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 24189400, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1342 Hs			1 448
+	Hs
		601882 ERBB3_HUMAN (1-1342): 0: 1388: 100.00		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		428019 ERBB3_HUMAN (1-1342): 0: 1388: 100.00		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		338265 EGFR_HUMAN (18-1157): 0: 1041: 42.30		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		338607 EGFR_HUMAN (18-1157): 0: 1041: 42.30		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		337782 EGFR_HUMAN (18-1157): 0: 1041: 42.30		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		338266 EGFR_HUMAN (18-1157): 0: 1041: 42.30		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		435607 IGF1R_HUMAN (577-1061): 4.71e-104: 363: 21.00		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		665575 EPHB2_HUMAN (635-993): 1.41e-105: 362: 28.00		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		665203 EPHA2_HUMAN (665-996): 4.18e-104: 356: 29.40		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		428109 EPHA4_HUMAN (656-996): 2.83e-103: 354: 27.79		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		872631 EPHA4_HUMAN (656-996): 2.83e-103: 354: 27.79		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		872702 EPHA4_HUMAN (656-996): 2.83e-103: 354: 27.79		TBB2B_HUMAN (1-440): 0: 694: 39.77
+	Gg
		94426 KSYK_CHICK (715-958): 2e-43: 170: 36.80		TBA2_CHICK (1-446): 0: 783: 83.41
+	Hs
		983628 FAK1_HUMAN (713-992): 4.43e-41: 167: 32.19		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Gg
		94429 KSYK_CHICK (715-958): 2e-43: 170: 36.80		TBB7_CHICK (1-439): 0: 697: 40.55
+	Rn
		544865 INSR_RAT (329-650): 1.42e-20: 101: 16.71		TBA4A_RAT (1-448): 0: 724: 100.00
+	Hs
		411416 INSR_HUMAN (329-650): 2.27e-22: 106: 16.98		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		411272 INSR_HUMAN (329-650): 2.27e-22: 106: 16.98		TBB5_HUMAN (1-439): 0: 697: 40.55