HitPredict

Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1342 Hs			1 602
+	Hs
		338320 EGFR_HUMAN (18-1157): 0: 1041: 42.30		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		338037 EGFR_HUMAN (18-1157): 0: 1041: 42.30		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		337444 ABL1_HUMAN (696-1307): 5.97e-133: 439: 22.51		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		434179 RET_HUMAN (518-1072): 1.47e-118: 399: 21.15		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		305100 EPHA4_HUMAN (656-996): 2.83e-103: 354: 27.79		RIMB1_HUMAN (21-511): 1.49e-43: 169: 14.76
+	Hs
		435621 IGF1R_HUMAN (577-1061): 4.71e-104: 363: 21.00		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Mm
		222845 ACK1_MOUSE (677-1328): 5.23e-124: 413: 21.75		MYH10_MOUSE (29-602): 1.93e-20: 98.3: 9.45
+	Mm
		222875 ACK1_MOUSE (677-1328): 5.23e-124: 413: 21.75		MYH9_MOUSE (5-481): 5.09e-16: 84.1: 12.68
+	Mm
		222882 ACK1_MOUSE (677-1328): 5.23e-124: 413: 21.75		MY18A_MOUSE (239-594): 7.08e-09: 61.1: 12.78
+	Hs
		1052829 FAK2_HUMAN (673-1201): 9.77e-104: 355: 25.96		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47
+	Hs
		411364 INSR_HUMAN (329-650): 2.27e-22: 106: 16.98		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		537734 INSRR_HUMAN (329-644): 4.31e-16: 86.4: 14.51		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		665375 EPHA3_HUMAN (691-978): 1.41e-41: 168: 34.13		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		983639 FAK1_HUMAN (713-992): 4.43e-41: 167: 32.19		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47