Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: LRIG1 (Q96JA1)
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)
Gene: LRIG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 15282549
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GF_recep_IV~LRR_4, GF_recep_IV~LRR_8, LRR_4~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1342
Hs

1 1093
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024