Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: PA2G4 (Q9UQ80)
Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1)
Gene: PA2G4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.713

The method score is based on:

Property Details
Experiments 19037095, 11708806, 11325528, 10682683, 15583694
Identification Methods affinity chromatography technology, two hybrid, pull down, coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0031625 - ubiquitin protein ligase binding
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1342
Hs

1 394
+ Hs
+ Hs
+ Rn

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Last updated: 15 Jul 2024