HitPredict

Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26975582
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1342 Hs			1 576
+	Hs
		554266 ERBB3_HUMAN (1-1342): 0: 1388: 100.00		MUC1_HUMAN (234-571): 1.36e-09: 63.1: 13.82
+	Hs
		339210 EGFR_HUMAN (18-1157): 0: 1041: 42.30		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		307492 EGFR_HUMAN (18-1157): 0: 1041: 42.30		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Hs
		554307 ERBB4_HUMAN (1-1162): 0: 1152: 50.94		MUC1_HUMAN (234-571): 1.36e-09: 63.1: 13.82
+	Hs
		383583 ERBB2_HUMAN (25-1222): 0: 1067: 39.95		MUC1_HUMAN (234-571): 1.36e-09: 63.1: 13.82
+	Hs
		337875 EGFR_HUMAN (18-1157): 0: 1041: 42.30		MUC1_HUMAN (234-571): 1.36e-09: 63.1: 13.82
+	Hs
		434196 RET_HUMAN (518-1072): 1.47e-118: 399: 21.15		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		434323 RET_HUMAN (518-1072): 1.47e-118: 399: 21.15		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		307509 EPHA2_HUMAN (665-996): 4.18e-104: 356: 29.40		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Hs
		337335 ABL1_HUMAN (696-1307): 5.97e-133: 439: 22.51		MUC1_HUMAN (234-571): 1.36e-09: 63.1: 13.82