Interactor 1: SDHB (P21912)
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip)
Gene: SDHB
Interactor 2: SDHA (P31040)
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp)
Gene: SDHA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.958 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37071682, 28514442, 33961781, 35235311, 26749241, 24606901, 19688755 |
| Identification Methods | cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, blue native page |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FAD_binding_2~Fer2_3, Fer2_3~Succ_DH_flav_C, FAD_binding_2~Fer4_17 |
| Common GO terms | GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0006099 - tricarboxylic acid cycle GO:0006121 - mitochondrial electron transport, succinate to ubiquinone GO:0008177 - succinate dehydrogenase (quinone) activity and 3 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Sc |   |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Hp | |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Nv | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
