Interactor 1: DRD5 (P21918)
D(1B) dopamine receptor (D(5) dopamine receptor) (D1beta dopamine receptor) (Dopamine D5 receptor)
Gene: DRD5

Interactor 2: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 9603210
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~G-alpha
Common GO terms GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 - activation of adenylate cyclase activity
GO:0007191 - adenylate cyclase-activating dopamine receptor signaling pathway
GO:0071870 - cellular response to catecholamine stimulus
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 477
Hs

1 394
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024