HitPredict

Interactor 1: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Interactor 2: ITA3 (P26006)
Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]
Gene: ITGA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	10694273, 10065872, 26686862
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0009897 - external side of plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 228 Hs			1 1051
+	Hs
		639879 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		ITA3_HUMAN (1-1051): 0: 1223: 100.00
+	Hs
		639875 CD151_HUMAN (3-222): 5.02e-51: 167: 30.08		ITA3_HUMAN (1-1051): 0: 1223: 100.00
+	Hs
		639894 TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02		ITA3_HUMAN (1-1051): 0: 1223: 100.00
+	Hs
		602217 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		ITA6_HUMAN (11-1043): 0: 1027: 35.75
+	Hs
		613235 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		ITA6_HUMAN (11-1043): 0: 1027: 35.75
+	Hs
		613229 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		ITA6_HUMAN (11-1043): 0: 1027: 35.75
+	Hs
		613224 CD151_HUMAN (3-222): 5.02e-51: 167: 30.08		ITA6_HUMAN (11-1043): 0: 1027: 35.75
+	Hs
		50294 TSN11_HUMAN (10-223): 3.63e-50: 165: 25.83		ITA6_HUMAN (11-1043): 0: 1027: 35.75
+	Hs
		819448 CD151_HUMAN (3-222): 5.02e-51: 167: 30.08		ITA7_HUMAN (1-1043): 0: 1001: 33.85
+	Hs
		50296 TSN11_HUMAN (10-223): 3.63e-50: 165: 25.83		ITA7_HUMAN (1-1043): 0: 1001: 33.85
+	Hs
		530541 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		ITA4_HUMAN (3-1050): 0: 898: 22.77
+	Hs
		419182 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		ITAV_HUMAN (30-1021): 0: 854: 25.26
+	Hs
		443039 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		ITA5_HUMAN (7-1038): 0: 819: 25.67
+	Hs
		443058 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		ITA5_HUMAN (7-1038): 0: 819: 25.67
+	Hs
		566851 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		ITA2_HUMAN (4-187): 2.16e-34: 145: 25.81
+	Hs
		566869 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		ITA2_HUMAN (4-187): 2.16e-34: 145: 25.81
+	Hs
		880206 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		ITA1_HUMAN (1-171): 1.12e-34: 146: 23.56
+	Hs
		91491 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		E7ESP4_HUMAN (4-187): 2.59e-34: 144: 25.81
+	Hs
		566893 TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02		ITA2_HUMAN (4-187): 2.16e-34: 145: 25.81
+	Hs
		595498 CD82_HUMAN (4-224): 3.81e-46: 155: 24.23		ITAL_HUMAN (11-190): 1.16e-29: 129: 22.22