HitPredict

Interactor 1: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	30833792, 11504738, 26186194, 28514442, 33961781, 26686862, 23289620
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 228 Hs			1 613
+	Hs
		905541 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		887922 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Mm
		728559 CD81_MOUSE (1-225): 2.11e-51: 168: 44.87		IGSF8_MOUSE (22-613): 1.44e-171: 503: 90.20
+	Hs
		653096 CD82_HUMAN (4-224): 3.81e-46: 155: 24.23		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		602290 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		905572 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		887973 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		446077 CD63_HUMAN (1-228): 1.71e-52: 170: 24.49		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		819474 CD151_HUMAN (3-222): 5.02e-51: 167: 30.08		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		1245273 TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		653105 CD82_HUMAN (4-224): 3.81e-46: 155: 24.23		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		237768 TSN2_HUMAN (3-228): 1.77e-44: 150: 46.46		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		602297 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		ROBO1_HUMAN (25-507): 1.65e-32: 136: 12.83
+	Hs
		888000 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		ROBO1_HUMAN (25-507): 1.65e-32: 136: 12.83
+	Hs
		253625 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		253639 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		253665 TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		1199563 TSN33_HUMAN (10-224): 1.17e-48: 162: 20.08		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		237786 TSN3_HUMAN (6-226): 2.32e-33: 122: 19.75		FGFR2_HUMAN (70-300): 6.05e-20: 96.4: 12.97