Interactor 1: DPOE (P21951)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POL2

Interactor 2: DPB2 (P24482)
DNA polymerase epsilon subunit B (DNA polymerase II subunit 2)
Gene: DPB2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 16369485, 23178807, 9792727, 11805826, 12015307, 12665575, 10878005, 14747467, 15824130, 25538242, 15163346, 11756442, 16554755, 16429126, 16916794, 30968138, 32415104, 18851837, 37730685, 37968396 and 5 others

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Identification Methods 3D electron microscopy, anti tag coimmunoprecipitation, two hybrid, tandem affinity purification, affinity chromatography technology, biochemical, x-ray crystallography, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_E_B~DUF1744
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006261 - DNA-templated DNA replication
GO:0008622 - epsilon DNA polymerase complex
GO:0042276 - error-prone translesion synthesis
and 1 others

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Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2222
Sc

1 689
+ Hs
+ Sp
+ Dm
+ Sc

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Last updated: 15 Jul 2024