Interactor 1: KCNA3 (P22001)
Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)
Gene: KCNA3

Interactor 2: KCNA5 (P22460)
Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5)
Gene: KCNA5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 18218624, 28514442, 33961781
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB_2~BTB_2, Ion_trans~Ion_trans
Common GO terms GO:0005251 - delayed rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0008076 - voltage-gated potassium channel complex
GO:0015271 - outward rectifier potassium channel activity
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 575
Hs

1 613
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+ Mm
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024