Interactor 1: KCNA3 (P22001)
Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)
Gene: KCNA3

Interactor 2: KCNA1 (Q09470)
Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1)
Gene: KCNA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 32296183, 10428084, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB_2~BTB_2, Ion_trans~Ion_trans
Common GO terms GO:0005251 - delayed rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0008076 - voltage-gated potassium channel complex
GO:0021554 - optic nerve development
GO:0022038 - corpus callosum development
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 575
Hs

1 495
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Last updated: 15 Jul 2024