HitPredict

Interactor 1: KCNA3 (P22001)
Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)
Gene: KCNA3

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	9341123
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 575 Hs			1 904
+	Hs
		608272 KCNA5_HUMAN (13-575): 5.99e-141: 423: 57.77		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Rn
		580271 KCNA5_RAT (13-575): 4.19e-149: 443: 57.78		DLG1_RAT (1-904): 0: 701: 92.54
+	Hs
		608224 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		608244 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		DLG3_HUMAN (139-904): 0: 585: 66.28
+	Rn
		548175 KCNA4_RAT (76-575): 8.52e-135: 408: 66.02		DLG3_RAT (99-904): 0: 590: 64.57
+	Hs
		602901 KCNA3_HUMAN (1-575): 0: 552: 100.00		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Mm
		558878 KCNA3_MOUSE (53-575): 1.84e-161: 472: 95.08		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Mm
		927733 KCNA2_MOUSE (53-575): 7.08e-145: 429: 71.16		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		558713 KCNA2_HUMAN (53-575): 1.15e-144: 428: 71.16		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		159156 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		608268 KCNA5_HUMAN (13-575): 5.99e-141: 423: 57.77		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Mm
		558703 KCNA1_MOUSE (53-575): 5.73e-142: 422: 68.00		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		608277 KCNA5_HUMAN (13-575): 5.99e-141: 423: 57.77		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		942333 KCNA1_HUMAN (53-575): 2.32e-141: 420: 67.81		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		608221 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		608230 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Rn
		548174 KCNA4_RAT (76-575): 8.52e-135: 408: 66.02		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Hs
		608231 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		DLG2_HUMAN (393-627): 7.26e-21: 100: 24.48
+	Hs
		608232 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80
+	Hs
		608222 KCNA4_HUMAN (80-575): 5.92e-137: 414: 66.67		EM55_HUMAN (161-314): 1.14e-14: 79.5: 14.56