HitPredict

Interactor 1: BMP6 (P22004)
Bone morphogenetic protein 6 (BMP-6) (VG-1-related protein) (VG-1-R) (VGR-1)
Gene: BMP6

Interactor 2: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 18070108, 10504300
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~TGF_beta
Common GO terms GO:0001649 - osteoblast differentiation
GO:0006955 - immune response
GO:0010628 - positive regulation of gene expression
GO:0030501 - positive regulation of bone mineralization
GO:0030509 - BMP signaling pathway
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 513
Hs

1 532
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024