HitPredict

Interactor 1: FNTB (P22007)
Protein farnesyltransferase subunit beta (FTase-beta) (PFTase beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)
Gene: RAM1

Interactor 2: FNTA (P29703)
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (PFTase/PGGTase I alpha) (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)
Gene: RAM2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 10688190, 11805826, 18719252, 26771498, 37968396, 16429126
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PPTA~Prenyltrans
Common GO terms GO:0004660 - protein farnesyltransferase activity
GO:0005965 - protein farnesyltransferase complex
GO:0018343 - protein farnesylation
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 431
Sc

1 316
+ Dm
+ Ce
+ Hs
+ Rn
+ Sp
+ At
+ Hs
+ Rn
+ Hs
+ Ce
+ Dm
+ Rn
+ Sc
+ Sc
+ Hs
+ Sp
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024