HitPredict

Interactor 1: POTEF (A5A3E0)
POTE ankyrin domain family member F (ANKRD26-like family C member 1B) (Chimeric POTE-actin protein)
Gene: POTEF

Interactor 2: CAP2 (P40123)
Adenylyl cyclase-associated protein 2 (CAP 2)
Gene: CAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~CAP_C
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1075 Hs			1 477
+	Hs
		474796 POTEI_HUMAN (1-1075): 0: 1112: 96.74		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		474807 POTEI_HUMAN (1-1075): 0: 1112: 96.74		CAP1_HUMAN (1-475): 0: 651: 62.71
+	Hs
		474868 POTEJ_HUMAN (1-1075): 0: 1062: 93.49		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		768462 ACTB_HUMAN (701-1075): 0: 584: 91.47		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		768466 ACTG_HUMAN (701-1075): 0: 584: 90.93		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		768474 Q1KLZ0_HUMAN (701-1075): 0: 584: 91.47		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		768467 ACTC_HUMAN (701-1075): 0: 579: 86.67		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		768468 ACTS_HUMAN (701-1075): 0: 578: 86.13		CAP2_HUMAN (1-477): 0: 698: 100.00
+	Hs
		891700 ACTB_HUMAN (701-1075): 0: 584: 91.47		CAP1_HUMAN (1-475): 0: 651: 62.71
+	Hs
		929826 ACTG_HUMAN (701-1075): 0: 584: 90.93		CAP1_HUMAN (1-475): 0: 651: 62.71
+	Hs
		932109 ACTC_HUMAN (701-1075): 0: 579: 86.67		CAP1_HUMAN (1-475): 0: 651: 62.71
+	Dm
		361193 ACT4_DROME (702-1075): 0: 628: 86.90		Q9VPX6_DROME (4-474): 0: 527: 43.73
+	Sc
		568336 ACT_YEAST (701-1075): 0: 628: 82.67		CAP_YEAST (3-474): 2.52e-178: 511: 33.92
+	Dm
		501544 ACT1_DROME (702-1075): 0: 582: 89.84		Q9VPX7_DROME (45-474): 0: 552: 48.03
+	Dm
		501500 ACT1_DROME (702-1075): 0: 582: 89.84		Q7KN55_DROME (4-474): 0: 551: 43.52
+	Dm
		361155 ACT2_DROME (702-1075): 0: 579: 89.31		Q9VPX7_DROME (45-474): 0: 552: 48.03
+	Dm
		501543 ACT1_DROME (702-1075): 0: 582: 89.84		Q9VPX6_DROME (4-474): 0: 527: 43.73
+	Dm
		501456 ACT5_DROME (702-1075): 0: 581: 88.24		Q9VPX6_DROME (4-474): 0: 527: 43.73
+	Dm
		862578 ACT3_DROME (702-1075): 0: 580: 87.70		Q9VPX6_DROME (4-474): 0: 527: 43.73
+	Dm
		361154 ACT2_DROME (702-1075): 0: 579: 89.31		Q9VPX6_DROME (4-474): 0: 527: 43.73