HitPredict

Interactor 1: SNF2 (P22082)
Transcription regulatory protein SNF2 (EC 3.6.4.-) (ATP-dependent helicase SNF2) (Regulatory protein GAM1) (Regulatory protein SWI2) (SWI/SNF complex component SNF2) (Transcription factor TYE3)
Gene: SNF2

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	17049045, 21749977, 23149935
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1703 Sc			1 136
+	Sc
		696239 STH1_YEAST (519-1654): 0: 797: 47.37		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		902117 ISW2_YEAST (592-1703): 0: 767: 27.27		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		696197 STH1_YEAST (519-1654): 0: 797: 47.37		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		229359 SMCA5_HUMAN (624-1531): 0: 741: 31.58		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Mm
		935460 SMCA5_MOUSE (654-1531): 0: 741: 32.43		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Hs
		229363 SMCA5_HUMAN (624-1531): 0: 741: 31.58		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Mm
		952763 SMCA5_MOUSE (654-1531): 0: 741: 32.43		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Mm
		952266 SMCA5_MOUSE (654-1531): 0: 741: 32.43		H32_MOUSE (1-136): 6.6e-61: 185: 88.97
+	Hs
		658647 SMCA1_HUMAN (660-1531): 0: 736: 32.21		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		658651 SMCA1_HUMAN (660-1531): 0: 736: 32.21		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		935262 CHD8_HUMAN (4-1702): 0: 724: 17.92		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952639 CHD8_HUMAN (4-1702): 0: 724: 17.92		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		934770 CHD4_HUMAN (754-1416): 0: 707: 34.41		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		935016 CHD5_HUMAN (719-1416): 0: 707: 32.74		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952343 CHD4_HUMAN (754-1416): 0: 707: 34.41		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1059646 CHD4_HUMAN (754-1416): 0: 707: 34.41		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		1086233 CHD5_HUMAN (719-1416): 0: 707: 32.74		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		1059677 CHD4_HUMAN (754-1416): 0: 707: 34.41		H3C_HUMAN (1-136): 8.2e-59: 179: 86.03
+	Hs
		229341 SMCA5_HUMAN (624-1531): 0: 741: 31.58		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		658641 SMCA1_HUMAN (660-1531): 0: 736: 32.21		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73