HitPredict

Interactor 1: FBRL (P22087)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin)
Gene: FBL

Interactor 2: WDR75 (Q8IWA0)
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)
Gene: WDR75

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0032040 - small-subunit processome
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 321
Hs

1 830
+ Hs
+ Ca
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Ca
+ Sc
+ Sc
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024