Interactor 1: FBRL (P22087)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin)
Gene: FBL

Interactor 2: NOP58 (Q9Y2X3)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 35271311, 26186194, 28514442, 29568061, 30540930, 34079125, 33961781, 37071682, 25470060, unassigned1655
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Fibrillarin~Nop, Fibrillarin~NOP5NT
Common GO terms GO:0001094 - TFIID-class transcription factor complex binding
GO:0001650 - fibrillar center
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 8 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 321
Hs

1 529
+ Hs
+ Sc
+ Ce
+ Sc
+ Ca
+ Pf
+ Ss
+ Af

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Last updated: 15 Jul 2024