HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: AP2B (P27351)
AP-2 complex subunit beta (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Clathrin assembly protein large beta chain)
Gene: APL1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32400111
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006886 - intracellular protein transport GO:0006897 - endocytosis
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 700
+	Hs
		925852 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2B1_HUMAN (1-699): 0: 583: 27.89
+	Rn
		509763 CLH1_RAT (4-1648): 0: 2901: 49.76		AP2B1_RAT (1-699): 0: 583: 27.89
+	Hs
		960765 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP1B1_HUMAN (1-700): 0: 556: 26.69
+	Hs
		212619 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP1G1_HUMAN (5-692): 3.91e-164: 494: 11.38
+	Mm
		567504 CLH1_MOUSE (4-1648): 0: 2909: 49.82		AP2A1_MOUSE (1-651): 3.82e-149: 460: 14.49
+	Hs
		321529 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2A1_HUMAN (1-665): 7.79e-149: 459: 14.15
+	Hs
		960775 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP3B2_HUMAN (22-647): 1.19e-147: 459: 17.06
+	Hs
		302138 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2A2_HUMAN (1-639): 1.42e-147: 455: 15.31
+	At
		1012804 CLAH1_ARATH (2-1642): 0: 2628: 43.39		APBLB_ARATH (3-699): 0: 553: 27.71
+	Sc
		604384 CLH_YEAST (1-1653): 0: 2506: 100.00		AP1B1_YEAST (16-606): 7.16e-134: 413: 24.17