HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: PAN1 (P32521)
Actin cytoskeleton-regulatory complex protein PAN1 (Mitochondrial distribution of proteins protein 3)
Gene: PAN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	32400111, 37968396, 16429126
Identification Methods	fluorescent resonance energy transfer, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0030479 - actin cortical patch
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 1480
+	Hs
		960975 CLH1_HUMAN (4-1648): 0: 2909: 49.76		EHD1_HUMAN (232-691): 9.44e-62: 223: 15.67
+	Hs
		960966 CLH1_HUMAN (4-1648): 0: 2909: 49.76		EHD4_HUMAN (232-695): 4.88e-58: 212: 14.72
+	Hs
		960815 CLH1_HUMAN (4-1648): 0: 2909: 49.76		ITSN1_HUMAN (44-1122): 3.88e-32: 139: 10.35
+	Hs
		787895 CLH1_HUMAN (4-1648): 0: 2909: 49.76		EPS15_HUMAN (139-487): 2.65e-18: 93.4: 16.91
+	Dm
		669597 CLH_DROME (4-1650): 0: 2804: 48.58		Q8T8W3_DROME (232-688): 1.89e-51: 193: 14.52
+	Dm
		112571 CLH_DROME (4-1650): 0: 2804: 48.58		M9ND00_DROME (260-1242): 1.36e-20: 101: 10.35
+	Ce
		712340 CLH_CAEEL (4-1650): 0: 2715: 46.52		Q9U2T9_CAEEL (260-537): 1.95e-12: 74.4: 15.74