HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: SLA2 (P33338)
Protein SLA2 (Transmembrane protein MOP2)
Gene: SLA2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	12181333, 18467557, 37968396
Identification Methods	two hybrid, protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0032051 - clathrin light chain binding GO:0048268 - clathrin coat assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 968
+	Hs
		148688 CLH1_HUMAN (4-1648): 0: 2909: 49.76		CTRO_HUMAN (216-968): 7.93e-72: 263: 14.38
+	Hs
		124394 CLH1_HUMAN (4-1648): 0: 2909: 49.76		HIP1_HUMAN (4-965): 1.95e-61: 229: 19.25
+	Hs
		255314 CLH1_HUMAN (4-1648): 0: 2909: 49.76		HIP1R_HUMAN (3-962): 5.64e-58: 218: 19.98
+	Hs
		237883 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP180_HUMAN (6-269): 1.74e-52: 200: 18.05
+	Hs
		960778 CLH1_HUMAN (4-1648): 0: 2909: 49.76		PICAL_HUMAN (6-348): 1.41e-51: 194: 15.73
+	Hs
		148571 CLH2_HUMAN (4-1635): 0: 2773: 48.90		CTRO_HUMAN (216-968): 7.93e-72: 263: 14.38
+	Hs
		124382 CLH2_HUMAN (4-1635): 0: 2773: 48.90		HIP1_HUMAN (4-965): 1.95e-61: 229: 19.25
+	Hs
		960906 CLH1_HUMAN (4-1648): 0: 2909: 49.76		MY18A_HUMAN (338-781): 3.03e-11: 70: 14.38
+	Hs
		237880 CLH2_HUMAN (4-1635): 0: 2773: 48.90		AP180_HUMAN (6-269): 1.74e-52: 200: 18.05
+	Hs
		863933 CLH2_HUMAN (4-1635): 0: 2773: 48.90		PICAL_HUMAN (6-348): 1.41e-51: 194: 15.73
+	At
		1012805 CLAH1_ARATH (2-1642): 0: 2628: 43.39		AP180_ARATH (6-444): 9.9e-57: 209: 13.19