Interactor 1: RPA2 (P22138)
DNA-directed RNA polymerase I subunit RPA135 (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (A135) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)
Gene: RPA135

Interactor 2: SPT5 (P27692)
Transcription elongation factor SPT5 (Chromatin elongation factor SPT5)
Gene: SPT5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 16908835, 12556496, 21467036
Identification Methods tandem affinity purification, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_1~Spt5-NGN, KOW~RNA_pol_Rpb2_6, KOW~RNA_pol_Rpb2_7
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1203
Sc

1 1063
+ Hs
+ Hs
+ Sc
+ Pf

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Last updated: 15 Jul 2024