HitPredict

Interactor 1: A5D6Q2 (A5D6Q2)
Ncoa3 protein
Gene: Ncoa3

Interactor 2: HNF4G (Q9WUU6)
Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2)
Gene: HNF4G

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	DUF4927~Hormone_recep, Hormone_recep~SRC-1
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1353 Mm			1 408
+	Mm
		985528 Q05BA5_MOUSE (1-1353): 1.49e-167: 540: 100.00		HNF4G_MOUSE (1-408): 2.33e-153: 441: 100.00
+	Hs
		782708 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		HNF4A_HUMAN (2-408): 1.98e-138: 405: 71.77
+	Mm
		60484 A5D6Q2_MOUSE (1-1353): 4.78e-168: 540: 100.00		ERR2_MOUSE (8-327): 2.25e-98: 301: 29.13
+	Mm
		985518 Q05BA5_MOUSE (1-1353): 1.49e-167: 540: 100.00		ERR2_MOUSE (8-327): 2.25e-98: 301: 29.13
+	Hs
		587212 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RXRA_HUMAN (5-332): 1.03e-116: 349: 42.09
+	Hs
		500381 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RARB_HUMAN (10-375): 9.23e-111: 334: 27.18
+	Hs
		490120 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		COT1_HUMAN (3-341): 5.7e-110: 331: 34.29
+	Hs
		530818 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RARG_HUMAN (10-363): 4.62e-102: 312: 25.07
+	Hs
		488043 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RARA_HUMAN (10-333): 1.35e-100: 308: 26.71
+	Hs
		370839 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ESR1_HUMAN (1-367): 1.49e-98: 307: 23.91
+	Hs
		320237 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ERR2_HUMAN (8-327): 4.69e-100: 306: 28.23
+	Hs
		782560 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		HNF4A_HUMAN (2-408): 1.98e-138: 405: 71.77
+	Hs
		611537 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NR4A1_HUMAN (2-331): 1.01e-92: 292: 26.16
+	Hs
		1025276 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NR1H3_HUMAN (3-324): 1.73e-91: 284: 25.07
+	Hs
		510047 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ERR1_HUMAN (5-327): 1.26e-91: 284: 27.51
+	Hs
		914652 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ERR3_HUMAN (5-327): 1.05e-104: 318: 28.27
+	Hs
		369703 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ESR1_HUMAN (1-367): 1.49e-98: 307: 23.91
+	Hs
		320210 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ERR2_HUMAN (8-327): 4.69e-100: 306: 28.23
+	Hs
		611451 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		NR4A1_HUMAN (2-331): 1.01e-92: 292: 26.16
+	Hs
		510022 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ERR1_HUMAN (5-327): 1.26e-91: 284: 27.51