HitPredict

Interactor 1: XRN1 (P22147)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (DNA strand transfer protein beta) (STP-beta) (KAR(-)-enhancing mutation protein) (Strand exchange protein 1) (p175)
Gene: XRN1

Interactor 2: NAM8 (Q00539)
Protein NAM8 (Nuclear accommodation of mitochondria protein 8) (U1 snRNP component NAM8)
Gene: NAM8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 21558325
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1528 Sc			1 523
+	Sc
		604966 XRN1_YEAST (1-1528): 0: 2262: 100.00		NGR1_YEAST (24-414): 5.36e-106: 333: 27.96
+	Sc
		376636 XRN1_YEAST (1-1528): 0: 2262: 100.00		PABP_YEAST (3-323): 4.49e-41: 157: 12.87
+	Hs
		1031389 XRN1_HUMAN (1-1257): 0: 1556: 33.64		PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11
+	Sc
		376906 XRN2_YEAST (1-798): 0: 892: 29.58		PABP_YEAST (3-323): 4.49e-41: 157: 12.87