HitPredict

Interactor 1: HSP74 (P22202)
Heat shock protein SSA4
Gene: SSA4

Interactor 2: HSP78 (P33416)
Heat shock protein 78, mitochondrial
Gene: HSP78

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	38551959, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity GO:0042026 - protein refolding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 811
+	Sc
		493577 HSP72_YEAST (1-642): 0: 947: 81.62		HSP78_YEAST (1-799): 0: 644: 100.00
+	Sc
		490781 HSP71_YEAST (1-642): 0: 941: 81.09		HSP78_YEAST (1-799): 0: 644: 100.00
+	Sc
		449992 HSP73_YEAST (1-642): 0: 935: 86.96		HSP78_YEAST (1-799): 0: 644: 100.00
+	Sc
		493413 HSP72_YEAST (1-642): 0: 947: 81.62		HS104_YEAST (1-809): 0: 554: 40.98
+	Sc
		490588 HSP71_YEAST (1-642): 0: 941: 81.09		HS104_YEAST (1-809): 0: 554: 40.98
+	Sc
		605312 HSP74_YEAST (1-642): 0: 936: 100.00		HS104_YEAST (1-809): 0: 554: 40.98
+	Sc
		449950 HSP73_YEAST (1-642): 0: 935: 86.96		HS104_YEAST (1-809): 0: 554: 40.98
+	Hs
		504728 HSP7C_HUMAN (2-642): 0: 953: 73.72		CLPB_HUMAN (498-811): 5.49e-70: 246: 35.59
+	Hs
		871771 HSP72_HUMAN (2-642): 0: 935: 72.63		CLPB_HUMAN (498-811): 5.49e-70: 246: 35.59
+	Sc
		495106 HSP72_YEAST (1-642): 0: 947: 81.62		RIX7_YEAST (357-762): 1.6e-24: 111: 12.26
+	Sc
		492612 HSP71_YEAST (1-642): 0: 941: 81.09		RIX7_YEAST (357-762): 1.6e-24: 111: 12.26