HitPredict

Interactor 1: HSP74 (P22202)
Heat shock protein SSA4
Gene: SSA4

Interactor 2: FES1 (P38260)
Hsp70 nucleotide exchange factor FES1 (Factor exchange for SSA1 protein 1)
Gene: FES1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	37968396, 23530227
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 290
+	Sc
		493800 HSP72_YEAST (1-642): 0: 947: 81.62		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Sc
		491027 HSP71_YEAST (1-642): 0: 941: 81.09		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Hs
		714085 HS71L_HUMAN (2-642): 0: 962: 71.30		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		564199 HSP76_HUMAN (4-642): 0: 954: 71.67		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		504872 HSP7C_HUMAN (2-642): 0: 953: 73.72		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Sp
		195082 HSP71_SCHPO (1-642): 0: 935: 79.19		FES1_SCHPO (1-237): 8.83e-52: 173: 29.63
+	Hs
		483807 HS71B_HUMAN (2-642): 0: 942: 73.32		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		871809 HSP72_HUMAN (2-642): 0: 935: 72.63		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13