HitPredict

Interactor 1: VATE (P22203)
V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 27 kDa subunit) (Vacuolar proton pump subunit E)
Gene: VMA4

Interactor 2: VATD (P32610)
V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D)
Gene: VMA8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.740

The method score is based on:

Property	Details
Experiments	11805826, 9195975, 16429126, 16774922, 22940862, 23071676, 37968396
Identification Methods	tandem affinity purification, biochemical, affinity chromatography technology, unspecified method
Interaction Type	physical association, association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0000329 - fungal-type vacuole membrane GO:0007035 - vacuolar acidification GO:0016471 - vacuolar proton-transporting V-type ATPase complex and 5 others more... GO:0033176 - proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0048388 - endosomal lumen acidification GO:0061795 - Golgi lumen acidification GO:1902600 - proton transmembrane transport
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	233
Sc

1	256

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024