HitPredict

Interactor 1: VATE (P22203)
V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 27 kDa subunit) (Vacuolar proton pump subunit E)
Gene: VMA4

Interactor 2: VATH (P41807)
V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 54 kDa subunit) (Vacuolar proton pump subunit H)
Gene: VMA13

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 19299516, 9195975, 16429126, 37968396, 16774922, 23071676
Identification Methods two hybrid, biochemical, affinity chromatography technology, unspecified method, tandem affinity purification
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_H_N~vATP-synt_E
Common GO terms GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 233
Sc

1 478
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024