Interactor 1: VATE (P22203)
V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 27 kDa subunit) (Vacuolar proton pump subunit E)
Gene: VMA4

Interactor 2: VATG (P48836)
V-type proton ATPase subunit G (V-ATPase subunit G) (V-ATPase 13 kDa subunit) (Vacuolar proton pump subunit G)
Gene: VMA10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 19081055, 23000382, 9334266, 20446876, 16774922, 23071676, 15751969, 12960158, 18955482, 34918374, 37968396, 23142977
Identification Methods molecular sieving, ion exchange chromatography, x ray scattering, pull down, affinity chromatography technology, far western blotting, two hybrid, unspecified method, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_G~vATP-synt_E
Common GO terms GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
and 5 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 233
Sc

1 114
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024