Interactor 1: RAD53 (P22216)
Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1)
Gene: RAD53
Interactor 2: DBF4 (P32325)
DDK kinase regulatory subunit DBF4 (Dumbbell forming protein 4)
Gene: DBF4
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.931 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10049915, 10964916, 27681475, 31515872, 34387546, 20835227, 21098477, 24285546, 12441400, 16107698, 20436286, 22130670, 23564203 |
| Identification Methods | two hybrid, biochemical, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Dfp1_Him1_M~FHA, Pkinase~zf-DBF |
| Common GO terms | GO:0003688 - DNA replication origin binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006270 - DNA replication initiation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
