Interactor 1: RAD53 (P22216)
Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1)
Gene: RAD53

Interactor 2: ASF1 (P32447)
Histone chaperone ASF1 (Anti-silencing function protein 1) (yASF1)
Gene: ASF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.55 0.734

The method score is based on:

Property Details
Experiments 11172707, 11331602, 9734355, 11805826, 11805837, 15755447, 12851493, 17130285, 20826334, 22323608, 19578373, 24573675, 16554755, 16303565, 27222517, 24824343, 25275495, 37968396, 20048053, 23184661 and 2 others

more...

Identification Methods affinity chromatography technology, coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, pull down, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006282 - regulation of DNA repair
GO:2000002 - negative regulation of DNA damage checkpoint
Homologous interactions 0

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Last updated: 15 Jul 2024