HitPredict

Interactor 1: TRX1 (P22217)
Thioredoxin-1 (Thioredoxin I) (TR-I) (Thioredoxin-2)
Gene: TRX1

Interactor 2: TSA2 (Q04120)
Peroxiredoxin TSA2 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 2) (cTPx 2) (Thiol-specific antioxidant protein 2) (Thioredoxin peroxidase type Ib) (TPx type Ib) (Thioredoxin-dependent peroxiredoxin TSA2)
Gene: TSA2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	1-cysPrx_C~Thioredoxin, AhpC-TSA~Thioredoxin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045454 - cell redox homeostasis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Sc			1 196
+	Hs
		495475 THIO_HUMAN (1-101): 1.14e-36: 121: 46.60		PRDX2_HUMAN (4-195): 6.97e-103: 296: 61.98
+	Mm
		956730 THIOM_MOUSE (5-101): 1.04e-32: 113: 36.00		PRDX2_MOUSE (4-195): 1.06e-102: 295: 61.98
+	Hs
		495510 THIO_HUMAN (1-101): 1.14e-36: 121: 46.60		PRDX1_HUMAN (4-193): 2.58e-98: 284: 58.64
+	Sc
		606199 TRX1_YEAST (1-103): 9.12e-42: 134: 100.00		TSA1_YEAST (1-195): 1.7e-91: 267: 86.15
+	Mm
		589514 THIOM_MOUSE (5-101): 1.04e-32: 113: 36.00		PRDX3_MOUSE (3-195): 1.28e-98: 287: 57.00
+	Hs
		685729 TXND5_HUMAN (7-101): 6.99e-27: 103: 26.73		PRDX2_HUMAN (4-195): 6.97e-103: 296: 61.98
+	Mm
		139927 THIOM_MOUSE (5-101): 1.04e-32: 113: 36.00		PRDX4_MOUSE (4-195): 9.51e-97: 283: 52.60
+	Mm
		727682 THIOM_MOUSE (5-101): 1.04e-32: 113: 36.00		PRDX1_MOUSE (4-193): 8.61e-98: 283: 58.64
+	Hs
		531737 PDIA4_HUMAN (3-103): 3.79e-25: 99.4: 22.02		PRDX3_HUMAN (2-195): 6.63e-101: 293: 56.70
+	Sc
		611720 TRX2_YEAST (1-102): 1.07e-37: 124: 78.64		TSA1_YEAST (1-195): 1.7e-91: 267: 86.15
+	Hs
		1026726 TXND5_HUMAN (7-101): 6.99e-27: 103: 26.73		PRDX4_HUMAN (4-195): 4.02e-96: 281: 53.13
+	Sc
		611752 TRX2_YEAST (1-102): 1.07e-37: 124: 78.64		TSA2_YEAST (1-196): 1.09e-88: 260: 100.00
+	Hs
		531815 PDIA4_HUMAN (3-103): 3.79e-25: 99.4: 22.02		PRDX4_HUMAN (4-195): 4.02e-96: 281: 53.13
+	Hs
		423216 PDIA1_HUMAN (3-101): 5.82e-25: 98.6: 23.59		PRDX4_HUMAN (4-195): 4.02e-96: 281: 53.13
+	Rn
		751965 PDIA4_RAT (3-103): 1.64e-23: 94.8: 22.02		PRDX4_RAT (4-195): 9.2e-97: 283: 52.60
+	Ss
		852832 THIO_SYNY3 (4-102): 6.1e-34: 114: 35.64		Y755_SYNY3 (3-194): 1.98e-89: 262: 44.56
+	So
		188731 TRXM_SPIOL (2-102): 1.56e-33: 115: 33.02		BAS1_SPIOL (3-194): 1.05e-87: 260: 49.22
+	Sc
		630634 TRX3_YEAST (2-101): 3.01e-36: 120: 46.00		PRX1_YEAST (3-195): 9.66e-69: 212: 27.32
+	Dm
		1177773 THIO2_DROME (1-102): 4.01e-35: 117: 43.81		Q7JX87_DROME (3-190): 3.03e-69: 211: 28.64
+	Ss
		852787 THIO_SYNY3 (4-102): 6.1e-34: 114: 35.64		P73348_SYNY3 (1-192): 3.6e-70: 214: 26.02