Interactor 1: VP37C (A5D8V6)
Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C)
Gene: VPS37C
Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15509564, 21757351, 25416956, 27609421, 32296183, 35271311, 24284069, unassigned1304 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Mod_r~Vps23_core |
| Common GO terms | GO:0000813 - ESCRT I complex GO:0010008 - endosome membrane GO:0016236 - macroautophagy GO:0031902 - late endosome membrane GO:0036258 - multivesicular body assembly and 6 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
