HitPredict

Interactor 1: TSH (P22265)
Protein teashirt
Gene: TSH

Interactor 2: ABDA (P29555)
Homeobox protein abdominal-A
Gene: abd-A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	21276241, 25869471, 30247122
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0007494 - midgut development GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 954 Dm			1 590
+	Dm
		606524 TSH_DROME (1-954): 0: 676: 100.00		UBX_DROME (286-464): 7.93e-37: 143: 40.58
+	Dm
		367175 TSH_DROME (1-954): 0: 676: 100.00		ANTP_DROME (300-478): 3.78e-36: 141: 38.17
+	Dm
		447317 TSH_DROME (1-954): 0: 676: 100.00		SCR_DROME (341-456): 2.09e-22: 101: 55.56
+	Dm
		668273 TIPT_DROME (1-860): 3.15e-120: 393: 31.84		ABDA_DROME (1-590): 6.66e-69: 235: 100.00
+	Dm
		950039 TIPT_DROME (1-860): 3.15e-120: 393: 31.84		UBX_DROME (286-464): 7.93e-37: 143: 40.58
+	Hs
		1144456 TSH3_HUMAN (433-903): 3.4e-17: 89.1: 15.57		VSX1_HUMAN (226-497): 8.04e-35: 137: 18.32
+	Hs
		1243832 KMT2C_HUMAN (241-918): 5.27e-09: 62.6: 12.78		LHX4_HUMAN (374-587): 8.68e-29: 120: 16.89
+	Hs
		882142 KMT2C_HUMAN (241-918): 5.27e-09: 62.6: 12.78		GSC_HUMAN (233-481): 3.72e-30: 120: 20.00