Interactor 1: IL6RA (P22272)
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)]
Gene: IL6RA
Interactor 2: IL6RB (Q00560)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: Il6st
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.646 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21057510 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | fn3~ig, IL6Ra-bind~ig, IL6Ra-bind~fn3, IL6Ra-bind~IL6Ra-bind, IL6Ra-bind~Lep_receptor_Ig |
| Common GO terms | GO:0004915 - interleukin-6 receptor activity GO:0005138 - interleukin-6 receptor binding GO:0005896 - interleukin-6 receptor complex GO:0008284 - positive regulation of cell population proliferation GO:0009897 - external side of plasma membrane and 6 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
