HitPredict

Interactor 1: RPC2 (P22276)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 130 kDa polypeptide)
Gene: RET1

Interactor 2: RPC8 (P35718)
DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III 25 kDa polypeptide) (RNA polymerase III subunit C25)
Gene: RPC25

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 11805826, 16429126, 30593915, 37968396, 21048197, 20887893, 14759368
Identification Methods tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rbc25~RNA_pol_Rpb2_7, RNA_pol_Rpb2_7~SHS2_Rpb7-N
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0006383 - transcription by RNA polymerase III
and 3 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1149
Sc

1 212
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024