Interactor 1: RFA1 (P22336)
Replication factor A protein 1 (RF-A protein 1) (DNA-binding protein BUF2) (Replication protein A 69 kDa DNA-binding subunit) (Single-stranded DNA-binding protein)
Gene: RFA1

Interactor 2: ATR (P38111)
Serine/threonine-protein kinase MEC1 (EC 2.7.11.1) (ATR homolog) (DNA-damage checkpoint kinase MEC1) (Mitosis entry checkpoint protein 1)
Gene: MEC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 14642562, 11805826, 16148046, 12967660, 31369547, 18922789, 20489023, 23355394, 16429126, 30224481, 37968396, 20190278
Identification Methods biochemical, coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0005634 - nucleus
GO:0006260 - DNA replication
GO:0006281 - DNA repair
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 621
Sc

1 2368
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024