HitPredict

Interactor 1: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: RNF41 (Q8BH75)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.528

Property	Details
Experiments	19483718
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 296 Mm			1 317
+	Mm
		607543 MYD88_MOUSE (1-296): 9.14e-132: 377: 100.00		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Mm
		607554 MYD88_MOUSE (1-296): 9.14e-132: 377: 100.00		TRAF3_MOUSE (6-132): 9.1e-28: 114: 24.62
+	Hs
		1306794 MYD88_HUMAN (15-296): 4.48e-123: 355: 83.69		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		1024747 MYD88_HUMAN (15-296): 4.48e-123: 355: 83.69		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78
+	Hs
		237506 TLR2_HUMAN (161-293): 9.64e-45: 163: 23.08		TRI58_HUMAN (3-307): 4.09e-54: 185: 15.69
+	Hs
		120189 TLR4_HUMAN (153-293): 4.24e-46: 167: 25.33		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Mm
		936285 TLR4_MOUSE (147-293): 3.19e-45: 165: 23.72		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Hs
		120151 TLR4_HUMAN (153-293): 4.24e-46: 167: 25.33		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78
+	Hs
		965965 ILRL1_HUMAN (144-296): 1.97e-45: 162: 17.22		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Mm
		1141445 TLR4_MOUSE (147-293): 3.19e-45: 165: 23.72		TRAF3_MOUSE (6-132): 9.1e-28: 114: 24.62
+	Hs
		886026 TIRAP_HUMAN (106-287): 2.59e-46: 157: 21.31		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		1342787 IL1AP_HUMAN (145-295): 1.3e-41: 152: 24.85		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		1024765 IL1AP_HUMAN (145-295): 1.3e-41: 152: 24.85		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78
+	Hs
		540406 IL1R1_HUMAN (154-295): 2.23e-38: 144: 14.02		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Mm
		936274 TLR3_MOUSE (160-293): 4.74e-36: 139: 20.83		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Hs
		179972 TLR3_HUMAN (160-293): 1.08e-35: 137: 20.14		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		179933 TLR3_HUMAN (160-293): 1.08e-35: 137: 20.14		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78
+	Hs
		1151863 SIGIR_HUMAN (157-294): 1.2e-30: 120: 23.33		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75