HitPredict

Interactor 1: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Interactor 2: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.952

The method score is based on:

Property Details
Experiments 25416956, 32296183, 9160889, 8576131, 17846119, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000430 - regulation of transcription from RNA polymerase II promoter by glucose
GO:0000432 - positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 23 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 310
Hs

1 310
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024