HitPredict

Interactor 1: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Interactor 2: SMCA1 (P28370)
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)
Gene: SMARCA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17846119, 21653943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Hs			1 1054
+	Hs
		229308 USF1_HUMAN (1-310): 3.09e-117: 342: 100.00		SMCA5_HUMAN (32-1051): 0: 1065: 81.86
+	Hs
		346003 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		SMCA1_HUMAN (1-1054): 0: 1130: 100.00
+	Mm
		1144922 TFE3_MOUSE (86-303): 2.04e-35: 136: 18.64		SMCA5_MOUSE (73-1051): 0: 1068: 84.88
+	Hs
		229271 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		SMCA5_HUMAN (32-1051): 0: 1065: 81.86
+	Hs
		607839 USF1_HUMAN (1-310): 3.09e-117: 342: 100.00		CHD8_HUMAN (2-1011): 0: 769: 27.72
+	Hs
		347406 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD5_HUMAN (31-961): 0: 800: 28.13
+	Hs
		1059888 MLXPL_HUMAN (87-303): 1.32e-36: 140: 18.55		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Mm
		348432 MYC_MOUSE (110-290): 4.19e-38: 142: 22.28		CHD4_MOUSE (29-960): 0: 787: 28.27
+	Hs
		346805 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Mm
		57188 TFE3_MOUSE (86-303): 2.04e-35: 136: 18.64		CHD7_MOUSE (3-1046): 0: 788: 26.74
+	Mm
		1144876 TFE3_MOUSE (86-303): 2.04e-35: 136: 18.64		CHD4_MOUSE (29-960): 0: 787: 28.27
+	Hs
		348113 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD7_HUMAN (3-1046): 0: 780: 26.74
+	Hs
		347951 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD8_HUMAN (2-1011): 0: 769: 27.72
+	Hs
		346938 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD9_HUMAN (2-1019): 0: 741: 26.94
+	Hs
		151469 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD2_HUMAN (21-1047): 0: 732: 29.60
+	Hs
		151368 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD1_HUMAN (5-1050): 0: 695: 29.33
+	Hs
		346268 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		SMCA4_HUMAN (60-913): 0: 686: 31.42
+	Mm
		348422 MYC_MOUSE (110-290): 4.19e-38: 142: 22.28		SMCA4_MOUSE (60-836): 0: 663: 35.23
+	Hs
		347218 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		CHD1L_HUMAN (183-755): 2.35e-132: 424: 43.06
+	Hs
		346267 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		SMCA2_HUMAN (170-669): 1.05e-122: 413: 44.32