HitPredict

Interactor 1: A5JYR4 (A5JYR4)
PID domain-containing protein
Gene: dab-1

Interactor 2: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.645

Property	Details
Experiments	23424658, 18298590, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Ce			1 1085
+	Ce
		1353620 NUMB1_CAEEL (18-417): 6.67e-72: 240: 16.75		Q9U2T9_CAEEL (1-1085): 6.1e-161: 506: 100.00
+	Hs
		833668 NUMB_HUMAN (16-401): 3e-85: 277: 16.24		EP15R_HUMAN (5-473): 6.97e-71: 256: 22.69
+	Hs
		787868 NUMB_HUMAN (16-401): 3e-85: 277: 16.24		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Mm
		788008 NUMB_MOUSE (16-401): 4.34e-84: 274: 16.00		EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78
+	Mm
		957141 DAB2_MOUSE (11-439): 3.16e-69: 237: 24.95		EP15R_MOUSE (5-477): 2.19e-56: 213: 21.52
+	Mm
		787999 DAB2_MOUSE (11-439): 3.16e-69: 237: 24.95		EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78
+	Hs
		269120 DAB1_HUMAN (13-491): 3.36e-80: 262: 22.71		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		557659 DAB2_HUMAN (11-447): 2.23e-68: 235: 24.53		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		208964 DAB1_HUMAN (13-491): 3.36e-80: 262: 22.71		NCK2_HUMAN (660-960): 3.34e-25: 110: 18.69
+	Mm
		223010 DAB1_MOUSE (13-491): 1.3e-78: 258: 21.80		NCK2_MOUSE (660-958): 2.72e-26: 114: 19.47
+	Rn
		924995 SHC1_RAT (30-476): 1.63e-95: 298: 13.67		GRB2_RAT (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		666186 SHC1_HUMAN (30-476): 6.62e-88: 282: 14.08		VAV3_HUMAN (875-1084): 4.84e-15: 82.1: 18.11
+	Hs
		924476 SHC2_HUMAN (29-475): 3.49e-91: 291: 13.36		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		666057 SHC1_HUMAN (30-476): 6.62e-88: 282: 14.08		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		924646 SHC4_HUMAN (9-476): 5.01e-87: 281: 12.58		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Mm
		957235 SHC1_MOUSE (30-476): 1.33e-86: 279: 13.25		GRB2_MOUSE (1030-1085): 5.12e-13: 71.3: 33.33
+	Hs
		269148 DAB1_HUMAN (13-491): 3.36e-80: 262: 22.71		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Mm
		956235 DAB1_MOUSE (13-491): 1.3e-78: 258: 21.80		NCK1_MOUSE (963-1085): 5.57e-14: 77.1: 21.82
+	Mm
		957157 DAB2_MOUSE (11-439): 3.16e-69: 237: 24.95		ITSN1_MOUSE (780-940): 1.48e-14: 81: 26.95
+	Mm
		957139 DAB2_MOUSE (11-439): 3.16e-69: 237: 24.95		GRB2_MOUSE (1030-1085): 5.12e-13: 71.3: 33.33