HitPredict

Interactor 1: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Interactor 2: GTF2I (P78347)
General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosomal region 6 protein)
Gene: GTF2I

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	1961251, 9384587, 16943425, 21653943
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 998
+	Hs
		346494 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		GTF2I_HUMAN (1-998): 0: 1555: 100.00
+	Hs
		379268 MYCN_HUMAN (106-286): 7.41e-35: 133: 19.13		GTF2I_HUMAN (1-998): 0: 1555: 100.00
+	Hs
		607844 USF1_HUMAN (1-310): 3.09e-117: 342: 100.00		GT2D1_HUMAN (571-975): 2.18e-31: 134: 23.30