HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 261
+	Hs
		609289 FGFR3_HUMAN (5-799): 0: 712: 61.07		LASP1_HUMAN (1-261): 1.82e-58: 188: 100.00
+	Hs
		608199 FGFR4_HUMAN (13-802): 0: 750: 100.00		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		608000 FGFR4_HUMAN (13-802): 0: 750: 100.00		SH319_HUMAN (189-261): 2.12e-13: 71.4: 35.62
+	Hs
		608105 FGFR4_HUMAN (13-802): 0: 750: 100.00		SRBS1_HUMAN (149-259): 7.54e-13: 69.9: 31.30
+	Hs
		609599 FGFR3_HUMAN (5-799): 0: 712: 61.07		DBNL_HUMAN (59-261): 2.02e-25: 105: 23.65
+	Hs
		609616 FGFR3_HUMAN (5-799): 0: 712: 61.07		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		508271 FGFR1_HUMAN (3-794): 0: 706: 54.76		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		508169 FGFR1_HUMAN (3-794): 0: 706: 54.76		SH3G1_HUMAN (48-261): 6.99e-24: 100: 18.81
+	Hs
		508089 FGFR1_HUMAN (3-794): 0: 706: 54.76		NOSTN_HUMAN (39-261): 9.75e-23: 98.8: 15.86
+	Hs
		507835 FGFR1_HUMAN (3-794): 0: 706: 54.76		PLCG2_HUMAN (15-261): 2.82e-22: 98: 13.77
+	Rn
		499160 FGFR1_RAT (3-794): 0: 698: 54.27		PLCG1_RAT (14-261): 1.2e-21: 96.1: 16.94
+	Hs
		508045 FGFR1_HUMAN (3-794): 0: 706: 54.76		SH319_HUMAN (189-261): 2.12e-13: 71.4: 35.62
+	Hs
		1072630 EPHA7_HUMAN (4-781): 0: 584: 19.90		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		872731 EPHA4_HUMAN (4-776): 0: 582: 19.47		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		562635 EPHA4_HUMAN (4-776): 0: 582: 19.47		PLCG2_HUMAN (15-261): 2.82e-22: 98: 13.77
+	Hs
		665684 EPHB2_HUMAN (4-779): 0: 557: 17.27		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		968350 ROR1_HUMAN (11-777): 2.13e-168: 512: 21.04		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		1081582 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		SH3G1_HUMAN (48-261): 6.99e-24: 100: 18.81
+	Hs
		562650 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		PLCG2_HUMAN (15-261): 2.82e-22: 98: 13.77
+	Rn
		499163 NTRK2_RAT (122-757): 1.27e-165: 501: 26.62		PLCG1_RAT (14-261): 1.2e-21: 96.1: 16.94