HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: CYFP2 (Q96F07)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: CYFIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045862 - positive regulation of proteolysis
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 1278
+	Hs
		508146 FGFR1_HUMAN (3-794): 0: 706: 54.76		CYFP2_HUMAN (1-1278): 0: 2164: 100.00
+	Hs
		1072571 EPHA7_HUMAN (4-781): 0: 584: 19.90		CYFP2_HUMAN (1-1278): 0: 2164: 100.00
+	Hs
		872688 EPHA4_HUMAN (4-776): 0: 582: 19.47		CYFP2_HUMAN (1-1278): 0: 2164: 100.00
+	Hs
		665645 EPHB2_HUMAN (4-779): 0: 557: 17.27		CYFP2_HUMAN (1-1278): 0: 2164: 100.00
+	Hs
		1081564 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		CYFP2_HUMAN (1-1278): 0: 2164: 100.00
+	Hs
		385332 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		CYFP2_HUMAN (1-1278): 0: 2164: 100.00
+	Hs
		1072531 EPHA7_HUMAN (4-781): 0: 584: 19.90		CYFP1_HUMAN (1-1277): 0: 2040: 85.92
+	Hs
		665619 EPHB2_HUMAN (4-779): 0: 557: 17.27		CYFP1_HUMAN (1-1277): 0: 2040: 85.92
+	Mm
		546306 NTRK2_MOUSE (122-757): 5e-166: 503: 26.62		CYFP1_MOUSE (1-1277): 0: 2032: 85.68
+	Hs
		385062 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		CYFP1_HUMAN (1-1277): 0: 2040: 85.92
+	Hs
		434226 RET_HUMAN (221-802): 2.33e-148: 465: 34.72		CYFP1_HUMAN (1-1277): 0: 2040: 85.92