HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005783 - endoplasmic reticulum
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 999
+	Hs
		609631 FGFR3_HUMAN (5-799): 0: 712: 61.07		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		508291 FGFR1_HUMAN (3-794): 0: 706: 54.76		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320811 FGFR3_HUMAN (5-799): 0: 712: 61.07		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320803 FGFR1_HUMAN (3-794): 0: 706: 54.76		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		609191 FGFR3_HUMAN (5-799): 0: 712: 61.07		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		665690 EPHB2_HUMAN (4-779): 0: 557: 17.27		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		665546 EPHA8_HUMAN (4-763): 0: 549: 19.79		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1072565 EPHA7_HUMAN (4-781): 0: 584: 19.90		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		968353 ROR1_HUMAN (11-777): 2.13e-168: 512: 21.04		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		665505 EPHA8_HUMAN (4-763): 0: 549: 19.79		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		1081658 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320817 EPHA8_HUMAN (4-763): 0: 549: 19.79		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		1081553 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320862 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320790 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		503438 FGFR3_HUMAN (5-799): 0: 712: 61.07		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		507880 FGFR1_HUMAN (3-794): 0: 706: 54.76		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		507924 FGFR1_HUMAN (3-794): 0: 706: 54.76		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		507836 FGFR1_HUMAN (3-794): 0: 706: 54.76		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		503499 EPHB2_HUMAN (4-779): 0: 557: 17.27		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42