HitPredict

Interactor 1: KCNA4 (P22459)
Potassium voltage-gated channel subfamily A member 4 (HPCN2) (Voltage-gated K(+) channel HuKII) (Voltage-gated potassium channel HBK4) (Voltage-gated potassium channel HK1) (Voltage-gated potassium channel subunit Kv1.4)
Gene: KCNA4

Interactor 2: DLG3 (Q92796)
Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)
Gene: DLG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 817
+	Rn
		548175 KCNA4_RAT (1-653): 0: 587: 96.03		DLG3_RAT (1-817): 0: 689: 95.17
+	Hs
		608224 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Hs
		602905 KCNA3_HUMAN (84-653): 3.65e-154: 459: 60.07		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Rn
		580271 KCNA5_RAT (44-636): 7.42e-156: 464: 55.28		DLG1_RAT (3-817): 0: 578: 61.42
+	Hs
		608272 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Dm
		439922 KCNAS_DROME (119-614): 2.75e-133: 407: 58.38		DLG1_DROME (46-817): 1.89e-166: 509: 49.35
+	Hs
		608221 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Rn
		548174 KCNA4_RAT (1-653): 0: 587: 96.03		DLG4_RAT (50-282): 1.36e-25: 115: 20.50
+	Mm
		1142574 KCNA4_MOUSE (1-653): 0: 576: 96.79		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Hs
		608231 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG2_HUMAN (312-547): 2.24e-16: 86: 21.40
+	Hs
		159156 KCNA4_HUMAN (1-653): 0: 595: 100.00		CSKP_HUMAN (106-261): 1.96e-14: 79.8: 16.88
+	Hs
		608232 KCNA4_HUMAN (1-653): 0: 595: 100.00		MPP7_HUMAN (101-229): 1.36e-13: 76.4: 16.28
+	Hs
		608222 KCNA4_HUMAN (1-653): 0: 595: 100.00		EM55_HUMAN (68-329): 1.24e-10: 66.7: 10.53
+	Hs
		602901 KCNA3_HUMAN (84-653): 3.65e-154: 459: 60.07		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Hs
		608268 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Mm
		927733 KCNA2_MOUSE (140-653): 1.88e-150: 446: 65.95		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Hs
		942333 KCNA1_HUMAN (140-653): 2.24e-150: 446: 65.56		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Hs
		558713 KCNA2_HUMAN (140-653): 4.02e-150: 445: 65.76		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Mm
		558703 KCNA1_MOUSE (140-653): 8.02e-150: 444: 65.56		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Mm
		558878 KCNA3_MOUSE (151-653): 1.09e-147: 440: 66.40		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25