HitPredict

Interactor 1: H1T (P22492)
Histone H1t (Testicular H1 histone)
Gene: H1-6

Interactor 2: PRP4K (Q13523)
Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)
Gene: PRP4K

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 1007
+	Hs
		559090 H15_HUMAN (1-119): 6.23e-20: 85.9: 59.66		PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00
+	Hs
		566285 H1T_HUMAN (1-207): 1.88e-40: 138: 100.00		KPCA_HUMAN (486-978): 6.58e-123: 391: 15.94
+	Hs
		558977 H15_HUMAN (1-119): 6.23e-20: 85.9: 59.66		KPCA_HUMAN (486-978): 6.58e-123: 391: 15.94
+	Hs
		559317 H13_HUMAN (1-150): 6.9e-20: 85.5: 49.33		KPCA_HUMAN (486-978): 6.58e-123: 391: 15.94
+	Rn
		413197 H1T_RAT (1-190): 2.51e-27: 104: 66.32		Q6P751_RAT (684-955): 1.02e-120: 372: 23.13
+	Hs
		408547 H15_HUMAN (1-119): 6.23e-20: 85.9: 59.66		KPCB_HUMAN (486-990): 2.48e-122: 390: 15.01
+	Hs
		559537 H12_HUMAN (33-150): 3.13e-18: 80.9: 55.93		KPCA_HUMAN (486-978): 6.58e-123: 391: 15.94
+	Hs
		408548 H12_HUMAN (33-150): 3.13e-18: 80.9: 55.93		KPCB_HUMAN (486-990): 2.48e-122: 390: 15.01
+	Mm
		794643 H11_MOUSE (1-125): 1.49e-18: 82: 59.20		CDK2_MOUSE (684-1005): 3.4e-126: 388: 23.40
+	Mm
		794656 H15_MOUSE (21-148): 3.43e-18: 81.2: 56.25		CDK2_MOUSE (684-1005): 3.4e-126: 388: 23.40
+	Rn
		88901 H11_RAT (1-124): 5.59e-19: 83.2: 58.87		KPCB_RAT (486-990): 1.11e-120: 386: 15.21
+	Hs
		414716 H15_HUMAN (1-119): 6.23e-20: 85.9: 59.66		CDK1_HUMAN (684-1005): 4.59e-124: 381: 25.00
+	Hs
		414717 H13_HUMAN (1-150): 6.9e-20: 85.5: 49.33		CDK1_HUMAN (684-1005): 4.59e-124: 381: 25.00
+	Rn
		88899 H11_RAT (1-124): 5.59e-19: 83.2: 58.87		CDK1_RAT (684-1005): 3.17e-124: 381: 25.00
+	Mm
		509472 H11_MOUSE (1-125): 1.49e-18: 82: 59.20		CDK1_MOUSE (684-1005): 4.99e-123: 378: 25.00
+	Hs
		558990 H15_HUMAN (1-119): 6.23e-20: 85.9: 59.66		CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45
+	Hs
		559328 H13_HUMAN (1-150): 6.9e-20: 85.5: 49.33		CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45
+	Rn
		88903 H11_RAT (1-124): 5.59e-19: 83.2: 58.87		Q6P751_RAT (684-955): 1.02e-120: 372: 23.13
+	Hs
		559065 H15_HUMAN (1-119): 6.23e-20: 85.9: 59.66		CDK5_HUMAN (684-1005): 2.54e-117: 363: 26.14
+	Mm
		794639 H11_MOUSE (1-125): 1.49e-18: 82: 59.20		CDK5_MOUSE (684-1005): 1.32e-117: 364: 26.14