HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: KALM (P23352)
Anosmin-1 (Adhesion molecule-like X-linked) (Kallmann syndrome protein)
Gene: ANOS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19696444
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	I-set~fn3, Ig_3~fn3, PK_Tyr_Ser-Thr~fn3
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 680
+	Hs
		665383 EPHA3_HUMAN (1-786): 0: 641: 20.68		EPHA5_HUMAN (390-669): 3.89e-24: 110: 9.19
+	Hs
		665374 EPHB2_HUMAN (1-788): 0: 624: 19.15		EPHA3_HUMAN (397-655): 2.1e-24: 111: 9.23
+	Hs
		665385 EPHA4_HUMAN (1-781): 0: 622: 20.78		EPHA3_HUMAN (397-655): 2.1e-24: 111: 9.23
+	Hs
		665399 EPHA3_HUMAN (1-786): 0: 641: 20.68		EPHA7_HUMAN (18-287): 1.04e-16: 86.6: 11.39
+	Hs
		616944 EPHA8_HUMAN (1-771): 0: 593: 20.56		PTPRD_HUMAN (108-530): 8.36e-28: 122: 11.66
+	Hs
		665605 EPHB2_HUMAN (1-788): 0: 624: 19.15		EPHA7_HUMAN (18-287): 1.04e-16: 86.6: 11.39
+	Hs
		872650 EPHA4_HUMAN (1-781): 0: 622: 20.78		EPHA7_HUMAN (18-287): 1.04e-16: 86.6: 11.39
+	Mm
		975145 EPHA4_MOUSE (1-781): 0: 626: 20.78		EPHA4_MOUSE (18-287): 7.78e-15: 80.5: 10.11
+	Hs
		665142 EPHA2_HUMAN (1-788): 0: 595: 21.50		EPHA3_HUMAN (397-655): 2.1e-24: 111: 9.23
+	Hs
		665184 EPHA2_HUMAN (1-788): 0: 595: 21.50		EPHA5_HUMAN (390-669): 3.89e-24: 110: 9.19
+	Mm
		872618 EPHB2_MOUSE (1-788): 0: 624: 19.03		EPHA4_MOUSE (18-287): 7.78e-15: 80.5: 10.11
+	Hs
		665244 EPHA2_HUMAN (1-788): 0: 595: 21.50		EPHA7_HUMAN (18-287): 1.04e-16: 86.6: 11.39
+	Hs
		665477 EPHA8_HUMAN (1-771): 0: 593: 20.56		EPHA7_HUMAN (18-287): 1.04e-16: 86.6: 11.39
+	Mm
		975146 EPHA2_MOUSE (1-788): 0: 579: 21.07		EPHA4_MOUSE (18-287): 7.78e-15: 80.5: 10.11
+	Hs
		665384 EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79		EPHA3_HUMAN (397-655): 2.1e-24: 111: 9.23
+	Hs
		872417 EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79		EPHA5_HUMAN (390-669): 3.89e-24: 110: 9.19
+	Hs
		872535 EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79		EPHA7_HUMAN (18-287): 1.04e-16: 86.6: 11.39
+	Hs
		1031989 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		PTPRS_HUMAN (140-531): 7.32e-23: 106: 11.86